PLINEST®
POLYNUCLEOTIDES
CELLULAR REJUVENATION · SKIN REPAIR
INJECTABLE TREATMENT
What are Polynucleotides?
Polynucleotides represent the next generation in skin rejuvenation. Derived from purified DNA fragments, they work at a cellular level to stimulate your skin's natural repair mechanisms.
Unlike traditional fillers or bio-remodelling treatments, polynucleotides activate fibroblasts – the cells responsible for producing collagen and elastin – resulting in genuine skin regeneration from within. Used around the eyes the increase collagen production and hydration.
WHY CHOOSE
The Benefits
✔︎ Stimulates cellular regeneration and repair
✔︎ Deep hydration at a cellular level
✔︎ Improves skin texture and tone
✔︎ Improves skin elasticity and firmness
✔︎ Reduces fine lines and wrinkles
✔︎ Can treat face, under-eyes and neck
YOUR JOURNEY
The Process
STEP 01
Consultation
A thorough skin assessment to
determine the best treatment plan for your skin concerns.
STEP 02
Treatment
Fine injections of polynucleotides into targeted areas*. The procedure
takes around 20–30 minutes.
STEP 03
Results
After 2–3 sessions, enjoy visibly
rejuvenated, firmer and
more radiant skin.
*Small bumps may appear under the skin for 24 - 72 hours after treatment.
INVESTMENT
PRICING
PLINEST®
£375
Per session
PLINEST® NEWEST
£375
Per session
PLINEST® EYES
£375
Per session
Prices include consultation. Course discounts available.
COMMON QUESTIONS
FAQ
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Polynucleotides (PN) are fragments of DNA derived from salmon or trout. When injected into the skin, they stimulate fibroblast activity, promoting the production of collagen and elastin for deep skin rejuvenation at a cellular level.
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While Profhilo uses hyaluronic acid to hydrate and bio-remodel, polynucleotides work at a DNA level to regenerate cells and repair damaged tissue. They are particularly effective for improving skin quality around delicate areas like the under-eyes.
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We typically recommend a course of 2 – 3 sessions spaced 3 – 4 weeks apart for optimal results. Maintenance treatments every 6 months help sustain the improvements.
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The treatment involves fine needle injections which cause minimal discomfort. Topical numbing cream is applied beforehand. The procedure takes around 20 – 30 minutes.
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Initial improvements in skin hydration can be seen within days. The full regenerative effects develop over 4 – 8 weeks as new collagen is produced.
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Side effects are minimal – slight redness, swelling or bruising at injection sites which typically resolve within 24 – 48 hours.
Ready to Rejuvenate Your Skin
Book a consultation to discover how Polynucleotides can transform your skin at a cellular level.

